Calcium Levofolinate

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

V03AF04

CAS registry number (Chemical Abstracts Service)

0080433-71-2

Chemical Formula

C20-H21-Ca-N7-O7

Molecular Weight

511

Therapeutic Categories

Antidote against folic acid antagonists

Detoxifying agent for antineoplastic treatment

Chemical Names

Calcium N-[p-[[[(6S)-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamate (1:1) (WHO)

Calcium (S)-2-{4-[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-ylmethylamino]benzoylamino}pentandisäure (IUPAC)

L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), (S)- (USAN)

Foreign Names

• Calcii levofolinas (Latin)
• Calcium levofolinate (German)
• Lévofolinate de calcium (French)
• Levofolinato calcico (Spanish)

Generic Names

• Calcium Levofolinate (OS: BAN)
• Levoleucovorin Calcium (OS: USAN)
• CL 307782 (IS)
• Elvorine (IS)
• Isovorin (IS)
• Levofolene (IS)
• Levofolinic acid, calcium salt (IS)
• LFA (IS)
• UNII-778XL9VBS8 (IS)
• Calcii levofolinas pentahydricus (PH: Ph. Eur. 6)
• Calcium Levofolinate Pentahydrate (PH: Ph. Eur. 6, BP 2010)
• Calciumlevofolinat-Pentahydrat (PH: Ph. Eur. 6)
• Lévofolinate calcique pentahydraté (PH: Ph. Eur. 6)

Brand Names

• Calcio Mefolinato Hexal
  Hexal, Italy



• Elvorine
  Wyeth, Belgium; Wyeth, France; Wyeth, Luxembourg



• Esvorin
  Opus®, Greece



• Folaxin
  Zambon, Spain



• Folivoran
  Vocate, Greece



• Fusilev
  Spectrum Pharmaceuticals, United States



• Isovorin
  Wyeth, United Arab Emirates; Wyeth, Bahrain; Wyeth, Denmark; Wyeth, Egypt; Wyeth, Spain; Wyeth, Finland; Wyeth, Greece; Wyeth, Iraq; Wyeth, Iran; Wyeth, Iceland; Wyeth, Jordan; Wyeth, Kuwait; Wyeth, Lebanon; Wyeth, Norway; Wyeth, Oman; Wyeth, Qatar; Wyeth, Saudi Arabia; Wyeth, Sweden; Wyeth, Syria; Wyeth, Yemen; Wyeth, South Africa; Wyeth KK, Japan; Wyeth Pharmaceuticals, United Kingdom



• Levofolic
  Medac, Greece; Medac, Slovakia



• Levofolinate
  Nippon Kayaku, Japan



• Raycept
  Zambon, Portugal



• Calcio Levofolinato Fidia
  Fidia, Italy



• Calcio Levofolinato Teva
  Teva, Italy



• Calciumlevofolinat Ebewe
  Ebewe, Austria; Ebewe, Indonesia; Ferron, Indonesia



• Divifolin
  Rottapharm, Italy



• Folanemin
  Bayer, Italy



• Foliben
  Firma, Italy



• Lederfolin
  Wyeth, Italy



• Levofolene
  Bayer, Italy



• Lévofolinate de Calcium Hospira
  Hospira, France



• Lévofolinate de Calcium Winthrop
  Sanofi-Aventis, France

International Drug Name Search

Glossary

BAN	British Approved Name
IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.